Latest News

  • RNA-Protein Complex Contributing To ‘Background Autoimmunity’ In Women

    Diagnostics World | The single biggest risk factor for autoimmune disease is being biologically a female and many explanations have been proposed as to why that is, among them sex hormones and the X chromosome with its large number of immune-related genes.

    Mar 21, 2024

  • Citizen-Driven Research Aids Development Of Digital Biomarkers For ALS

    Diagnostics World | When it comes to research on amyotrophic lateral sclerosis (ALS), every stakeholder—most especially patients—knows time is of the essence. From diagnosis to death, life expectancy from the debilitating neuromuscular disease can be two years or less.

    Mar 20, 2024

  • Trial Begins For ‘Probabilistic Approach’ To Diagnosing Ovarian Cancer

    Diagnostics World | Scientists in the Georgia Tech Integrated Cancer Research Center (ICRC) are proposing a new, more realistic approach to diagnosing cancer that provides a probabilistic statement about the likelihood of developing it, much like how cholesterol tests are used to assess heart disease risk. Probabilities are based on an individual’s metabolic profile and the first population group to be targeted are women at high risk for ovarian cancer.

    Mar 19, 2024

  • Biology-Based Diagnostic Criteria For Parkinson’s Disease Research

    Diagnostics World | Scientists from a trio of countries are calling for a new, more comprehensive way of classifying Parkinson’s disease for diagnostic research purposes that considers an individual’s biology. The disorder might thereby be detected before patients have any symptoms, as is now the case for cancer and diabetes.

    Mar 14, 2024

  • Proteomics Approach Working Its Way To The Clinic For Stubborn Cancers

    Diagnostics World | For roughly half of patients with recurrence of often-deadly glioblastoma multiforme (GBM), their tumors are characterized by cells that look a lot like healthy neurons. The mimicry trick was discovered by proteomics, which has opened a view to tumor alterations unavailable through genetics alone.

    Mar 12, 2024

  • GO Chip Finds Biomarkers Of Response To Lung Cancer Treatment

    Diagnostics World | Biomedical engineers have a significant role to play in the development and optimization of liquid biopsies to further precision oncology. Although molecular profiling of tumors has entered mainstream clinical practice, the wait time for identifying the best treatment for individual patients could be shortened by blood-testing devices designed to efficiently capture circulating tumor cells (CTCs) and cancer-specific protein markers on their surface.

    Mar 7, 2024

  • Priming Agents Could Take Liquid Biopsies To A Whole New Level

    Diagnostics World | A team of researchers from Massachusetts Institute of Technology (MIT) and the Broad Institute of MIT and Harvard are developing priming agents to temporarily boost levels of cell-free DNA (cfDNA) for cancer diagnostics. It’s an entirely new concept that could do for liquid biopsies what contrast agents have done for ultrasound and MRI.

    Mar 6, 2024

  • ‘Fragmentomics’ Approach Catches Cancers Earlier In The Blood

    Diagnostics World | A machine learning method dubbed A-PLUS (Alu Profile Learning Using Sequencing) recently demonstrated its ability to pick up cancers earlier and with smaller blood draws than is required for whole genome sequencing. This makes possible a future where people might get annual blood draws to check for cancer based on the “fragmentation pattern” of cell-free DNA (cfDNA) circulating in their blood.

    Mar 5, 2024