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IC3D — “Droplet by Droplet” to Single Target Sensitivity
The most critical challenge of assessing rare targets in large-size samples is how to overcome the problems of (1) finding the needle in a haystack, and (2) extremely low signal-to-noise ratio. With the exceedingly low abundance of the targets against the immense “swamp” of the background, any faint signal by the targets is probably swamped by the background chatter. In the IC3D technology, we have two “magic tricks” working in tandem to solve this long-standing challenge.