June 26, 2024 | PacBio, in collaboration with the international Consortium for Long-Read Sequencing (CoLoRS), announced the launch of the first publicly available and free HiFi long-read variant frequency database with global representation; PathAI unveiled two novel AI products, PathExplore Immuno-Oncology Profiling (IOP) and IHC Explore1; , Thermo Fisher Scientific has introduced One Lambda HLA PRO, an automated, modular pipetting system that offers versatility by accommodating different workflows on a single instrument, allowing laboratories to automate multiple human leukocyte antigen (HLA) and antibody testing technologies cost-effectively; more.
Illumina has appointed Everett Cunningham as Chief Commercial Officer (CCO). Cunningham will be responsible for building, guiding, and managing the company's global commercial organization. He brings extensive commercial experience across the healthcare tech, life sciences, and pharmaceutical industries. Most recently, Cunningham served as Chief Commercial Officer at Exact Sciences, where he oversaw the company's marketing, sales, and customer service functions. Prior to Exact Sciences, he held various senior leadership roles at Quest Diagnostics, GE Healthcare, and Pfizer, where he spent 21 years as a commercial leader. Press release.
PacBio, in collaboration with the international Consortium for Long-Read Sequencing (CoLoRS), announced the launch of the first publicly available and free HiFi long-read variant frequency database with global representation. This innovative resource fills a critical void for rare disease researchers, providing access to genetic variants that are not detectable through short-read sequencing methods. By enabling the filtering of common structural variants from long-read sequencing data, this database allows for the identification of rare and novel variants in rare disease cases. The launch of this database better enables researchers to utilize long-read genomic data to advance human health research. Press release.
PathAI unveiled two novel AI products, PathExplore Immuno-Oncology Profiling (IOP) and IHC Explore1, to empower cancer drug developers and clinical researchers with AI-powered insights. The product pairing provides unprecedented single-cell and spatial resolution of the tumor microenvironment from routine pathology samples to facilitate biomarker discovery and deeper understanding of treatment response for the next generation of cancer therapeutics. PathExplore IOP expedites characterization of immune phenotypes by quantifying tumor infiltrating lymphocytes and their spatial distribution using routine hematoxylin and eosin samples. PathExplore IOP was designed specifically to quantify patterns of immune infiltration characteristic of a strong immune response, and ultimately improved patient survival. Press release.
To enhance transplant laboratory productivity and efficiency, Thermo Fisher Scientific has introduced One Lambda HLA PRO, an automated, modular pipetting system that offers versatility by accommodating different workflows on a single instrument, allowing laboratories to automate multiple human leukocyte antigen (HLA) and antibody testing technologies cost-effectively. The instrument can also be configured to enable a LABScan3D advanced multiplex analyzer to be connected, supporting the automation process from set up to the reading of the tray. Product details.
Sapio Sciences announced Sapio Good Manufacturing Practice (GMP) LIMS for laboratories that require unparalleled flexibility to meet manufacturing compliance standards. The new Sapio GMP LIMS solution addresses industry applications in biotechnology, pharmaceutical, clinical research and diagnostics, food and beverage, chemical, and environmental testing. The three key elements include: Sapio QC LIMS, which streamlines material and product management with configurable dashboards, drug product registration, and batch creation; Sapio Environmental Monitoring Programs, which enhances site, equipment, and storage management by tracking and organizing manufacturing sites, equipment details, and hierarchical storage units; and Sapio Stability Management, which streamlines the setup and execution of stability studies. Press release.
Bio-Rad Laboratories launched the ddSEQTM Single-Cell 3' RNA-Seq Kit and complementary Omnition v1.1 analysis software for single-cell transcriptome and gene expression research. Designed to be run on Bio-Rad’s droplet-based single-cell isolation system, the ddSEQ Cell Isolator, the ddSEQ Single-Cell 3' RNA-Seq Kit delivers high-quality single-cell 3' RNA-Seq libraries in a fast, efficient, and affordable workflow, allowing researchers to easily conduct single-cell gene expression and regulation analyses. These valuable insights into single-cell transcription and gene expression support a broad range of research fields such as oncology, immunology, neurology, and stem cell biology. Press release.
Salesforce announced the general availability of Life Sciences Cloud, a platform for pharmaceutical and medical technology organizations to help personalize patient and healthcare professional (HCP) engagement and streamline clinical operations with data, automation, and trusted AI. Some features include: participant recruitment and enrollment, patient benefits verification, patient program outcome management, and more. Press release.
Epigenica unveiled its EpiFinder Platform with a patented high-throughput, multiplexing, quantitative ChIP-seq (hmqChIP-seq) technology and launched EpiFinder Genome for comprehensive genome-wide profiling. EpiFinder Genome, the company's flagship product and the first commercial kit of its kind, simultaneously targets up to eight markers in up to 24 samples or independent replicates, generating quantitative data for in-depth insights into biomedical research, drug discovery and development, diagnostics, and precision medicine. Some features and benefits include high-quality data, easy to use pooled workflow, validated with cells and tissue, and more. Press release.
NTT announces a new method to easily visualize the skill of patients’ hands and feet, which was previously difficult to quantify, by examining the cyclical motion of a smartphone for a short period of time. By using this method to evaluate the movement variability of children and the elderly, it became clear that skill changes with age, and it became possible to evaluate one's skill level relative to individuals of the same age. In addition, forced use of the right hand affected the relative skill of the left and right hands. Surprisingly, this forced correction affected the relative skill between the left and right feet as well. The development of this research is expected to contribute to the visualization of the recovery process through exercise rehabilitation in the medical and nursing fields, as well as to quantify the effects of training during sports activities. Press release.
Leica Microsystems has released version 14 of Aivia, its flagship image analysis solution. This update introduces a suite of new features and enhancements for accurate deep-learning based cell segmentation, automated phenotyping, and spatial data analysis in 3D multiplexed images. Researchers and scientists can visualize up to 15 channels in 3D multiplexed images simultaneously, providing a comprehensive view of complex biological processes. Aivia’s improved deep learning model accelerates cell detection by up to 78%, resulting in faster and more accurate detection and partition of cells. Press release.
Amid growing concerns from U.S. federal, state and local agencies over Highly Pathogenic Avian Influenza (HPAI) A (H5N1) detections in dairy cows, Integrated DNA Technologies launched the Avian Influenza Type A (H5) Primers and Probe Set to enable researchers to identify, target, and trace the presence of clade 2.3.4.4b of the H5N1 virus across bird, environmental, dairy cow, and poultry farm samples. The new offering is available for online ordering through IDT’s Tech Access Program, which enables access to the most advanced research tools in development to accelerate innovation. IDT’s Avian Influenza A (H5) Primers and Probe Set is manufactured in a certified, template-free environment and includes an internal control to help confirm false negatives. An Avian Influenza Positive Sample Control is also available for purchase. Press release.
Genialis announced a new partnership with the Pancreatic Cancer Action Network (PanCAN) to expand the validation of the Genialis krasID biomarker in the pancreatic cancer histology. Genialis krasID is a new artificial intelligence classifier that accurately predicts response and clinical benefit to KRAS inhibitors across preclinical, clinical, and real-world settings. Press release.
Personalis announced the commencement of commercialization efforts by Tempus for NeXT Personal, Personalis’ ultra-sensitive, whole genome-based liquid biopsy assay for detection of minimal residual disease (MRD) and recurrence in cancer. Members of Tempus’ commercial team can now engage in discussions with doctors about the use of the NeXT Personal Dx test for breast and lung cancers, as well as immunotherapy monitoring across all solid tumors. Press release.
QIAGEN and Myriad Genetics announced they will develop a globally distributable kit-based test for analyzing Homologous Recombination Deficiency status. This next-generation sequencing test aims to support research into personalized medicine in multiple solid tumor types, including ovarian cancer, and is expected to enhance decentralized testing capacities once a regulated product is developed with pharmaceutical partners. The project builds on the recently announced master collaboration agreement between the two companies. Press release.
Complete Genomics opened its Customer Experience Center demonstration lab near Boston’s biotech hub. The new lab, located in Framingham near Boston, is Complete Genomics’ first footprint on the East Coast and is expected to enable faster service and support to East Coast customers. Current and prospective customers in Boston and the greater northeast will be able to experience Complete Genomics’ DNBSEQ workflows including next-generation sequencing platforms, sample prep automation systems, and bioinformatics products. Press release.